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This
section provides
a selection of projects that your instructor may ask you to do before
class, during class, or after class on the topic of organ transplantation
and body part manufacture. These activities may be assigned to individuals
or groups of students.
Even
if these activities are not required, thinking about the issues
they raise may better prepare you for class discussion, writing
assignments, or an exam.
Please
send comments, suggestions, or ideas for additional individual or
group projects to choices@vt.edu.
Download
Complete Exercises as PDF File

Background
Activities
Organ
Donation in the United States Today
Bioethics Tutorial
History: Case Studies in Health Care Resource
Allocation
Health Care Resource Allocation in Film
Issues in Animal Welfare
Organ
Donation in the United States Today
Use the discussion
board available through your course homepage at http://www.learn.vt.edu
or contact choices@vt.edu to
reserve NetForum space.
Take this quiz
developed by TransWeb: All About Transplantation and Donation
(www.transweb.org),
a nonprofit educational web site serving the world transplant community
to see how much you already know about organ transplantation
in the US:
http://www.transweb.org/myths/quiz.htm
Next, review
the data available through UNOS: United Network for Organ Sharing
(www.unos.org)
about organ donation in the US today:
http://www.unos.org/Newsroom/Frame_news.asp?SubCat=critdata
Now, explore
the practice of organ donation through the Gift of Life organization's
website:
http://www.donors1.org/donation/donation.html
Make sure to
explore each of the 9 sub-sections: history, myths, fast facts,
FAQs, religious views, area transplant centers, organs and tissues,
family discussion, and donor recognition.
Finally, participate
in an online discussion on the following topic:
What decisions
have you and your loved ones made about organ donation? Are you
planning to donate your organs in case of death? When a loved
one dies, will you make the decision to donate his or her organs?
Would you consider donating a kidney as a living donor?
Please treat
your classmates with the same respect that you would show them within
a classroom situation.
Bioethics Tutorial
Part I: Approaches
First
read:
Thinking
Ethically: A Framework for Moral Decision Making
Developed by Manuel Velasquez, Claire Andre, Thomas Shanks, S.J.,
and Michael J. Meyer, Markkula Center for Applied Ethics at Santa
Clara University http://www.scu.edu/SCU/Centers/Ethics/practicing/decision/thinking.html
This reading
describes five approaches to ethical decision-making: utilitarian;
rights-based (also called deontological); fairness or justice; common
good; or virtue. A sixth approach, dominant in the field of bioethics,
is called principlism or principle-based bioethics. Read more about
this approach in a primer developed by Thomas R. McCormick, faculty
at the University of Washington School of Medicine:
Principles
of Bioethics
http://eduserv.hscer.washington.edu/bioethics/tools/princpl.html
Next, choose
one of the scenarios below, and evaluate the situation using each
of the six ethical decision-making frameworks:
- The father
of a 30 year old man died of Huntington's Disease at age 38. Huntington's
Disease is a hereditary illness causes by a single genetic error
(see http://www.hdsa.org/
and http://www.hdac.org/hdfaq/faq.php)
that results in neurodegeneration and early death. The 30 year
old man refuses to be tested for the defect before conceiving
children with his wife; who does not know about the death of the
man's father, or the possibility that her husband also carries
the gene for Huntington's Disease. Each child of a parent with
Huntington's Disease stands a 50% chance of inheriting the disease.
Should a medical professional notify the man's wife, force the
man to be tested, or respect the man's right to privacy and autonomy?
- An infectious
agent that looks like smallpox is released in a rural town with
limited medial expertise and equipment. Federal workers want to
quarantine the area and refuse to allow medical equipment or professionals
into the town, or any town residents to leave. Medical groups
want to access the town, to save as many people as possible. People
who do not yet have smallpox want to leave. What should be done
and who should decide?
- Fluoridation
the practice of adding fluoride to the public water supply
has been an accepted practice in the United States for
over 50 years. Fluoride is believed by many (including the American
Dental Association) to significantly reduce tooth decay in the
population. (See http://www.ada.org/public/topics/fluoride/fluoride.html)
However, opponents point to an increase in fluoride overdose resulting
in the poisoning of young children, crippling skeletal fluorosis
in the population at large, and detrimental environmental impacts.
Opponents are particularly concerned by what they see as a lack
of individual choice. (See http://www.fluoridation.com/)
Should communities continue to fluoridate their water?
- A 25 year
old woman tests positive for a highly contagious sexually transmitted
disease for which there is currently no cure however, early
treatment significantly decreases health risk and increases quality
of life. The woman has had over 20 sexual partners within the
last three years, including a number of persons with whom she
has practiced unsafe sex. The woman indicates that she does not
plan to contact any of her former partners, nor will she provide
her physician or the health department with their names, to urge
them to be tested. Should the woman be legally required to provide
the names of all her partners?
Part II: Organ Transportation
Next, read this
primer on some of the particular ethical issues associated with
organ transplantation, developed by the Science Museum of Virginia:
http://www.smv.org/prog/B2Kprimorgtrans.htm
Now, examine
these case studies on organ donation focused on the ethics
of resource allocation.
http://www.med.howard.edu/ethics/handouts/lecture13.htm
Using the bioethical
approaches you learned above, evaluate these two cases and produce
written recommendations.
History: Case Studies in Health Care Resource
Allocation
Write a book
review choose one of the following books or a text selected
or approved by your instructor. Length: 750-1000 words
David Rothman,
Beginnings Count: The Technological Imperative in American
Health Care (Oxford University Press: 1997).
David Rothman,
Strangers at the Bedside: A History of How Law and Bioethics
Transformed Medical Decision Making (Basic Books: 1991).
Lisa Belkin,
First Do No Harm (Fawcett Books: 1994).
How to Write
a Critical Book Review (pdf)
Health Care Resource Allocation in Film
Write a film
review focusing, in part, on health care resource allocation
choose one of the following films or one selected or approved by
your instructor. Length: 750-1000 words
First Do
No Harm (Touchstone Video: 1997)
John Q
(New Line Productions: 2002)
Lorenzo's
Oil (Universal Studios: 1993)
Miss Evers'
Boys (HBO Studios: 1997)
Issues in Animal Welfare
What is the
relationship between humans and other animals? What does the human/animal
relationship look like in the arena of scientific research? What
should it look like?
This exercise
can be done with a partner or by yourself review the articles
below, supplementing them with additional research as you identify
the need and then develop a set of dialogue papers between
an opponent of animal research and a supporter of continued animal
research. Each paper should be done in an op-ed style see
a description of what an op-ed looks like below.
The Center
for Laboratory Animal Welfare
http://www.labanimalwelfare.org/
"Trends
in Animal Research: Increased concern for animals, among scientists
as well as the public, is changing the ways in which animals are
used for research and safety testing" Madhusree Mukerjee,
Scientific American, February 1997
http://www.animalliberationfront.com/Philosophy/Scien%20Amer.htm
What does
an op-ed look like?
In these papers
you should give a brief introduction explaining the controversy
over animal research, identify the key issues, and offer your own
position on what ought (or ought not) be done, and then explain
why.
To make the
most convincing case, it is necessary not only to give the arguments
in support of your own position but also to identify what the opposing
arguments are (doing this fairly, of course) and to show why your
arguments are stronger or more reasonable.
Recognizing
areas of uncertainty and offering suggestions for what new policies
or laws might be useful are also appropriate.
Keep in mind
that op-ed articles are written for a general audience so you must
keep your op-ed paper simple and direct. You can be dramatic, poetic,
passionate. But avoid technical language. Keep sentences short and
clear. And it helps to end your op-ed paper with a brief, snappy
paragraph that sums up your view.
Each paper should
be no longer than 750 words, double-spaced with pages numbered.
You must give credit to any sources that you use including the Internet.
In the case-study paper you can do this with footnotes. However,
op-ed articles do not use footnotes. So here, you must work the
credit into the text. For example, you could write something like:
"According to Jill Hudson in her November 1999 article in Discover
magazine
"
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Discussion
Activities
Religious
Traditions Making Decisions about Donation
Informed Consent should it be presumed
or voluntary in the United States?
Animal-to-Human Organ Transplantation
Peril or Promise?
A Presidential Commission on Embryonic Stem
Cells
Organ and Body Part Manufacture and Repair
Religious
Traditions Making Decisions about Donation
What
do different religions have to say about the ethics of organ transplantation?
As a medical counselor, how would you talk to the families of potential
organ donors? Using the resources below and additional
research, as you see fit you, or you and a partner,
should develop a 3-5 page basic script about the benefits of organ
donation, and how you would handle specific questions and resistances
of the potential organ donor's family.
In
addition to using your background knowledge on organ transplantation
in the United State today, as well as any other information you
feel to be relevant, make sure to address specific religious doctrines.
General
Judaism
Christianity
Islam
Informed Consent should it be presumed
or voluntary in the United States?
In the United
States, organ donation functions on a voluntary consent basis,
meaning that the donor or his/her family must give permission
for organs to be donated. In other countries such as France
organ donation functions on a presumed consent basis
persons must opt out of organ donation, rather than into the process.
Option
1: If you are working alone, you are the chair of a science
advisory committee that will be established to advise the President
of the United States on the issue of consent in organ transplantation.
Should consent in the United States remain voluntary, or does
it make sense to switch to presumed consent?
As chair,
you must establish the parameters of the study what are
the issues? What other countries will be used as additional case
studies? Who else should be nominated to the advisory committee?
Option
2: If you are working in a group you will be producing
a 5-7 page report to advise the President. First, decide: what
are the issues? What other countries will be used as additional
case studies? Who else should be nominated to the advisory committee?
Then, choosing
both scientific and non-scientific roles for the advisory committee,
work with your group to answer the question. (Each person should
be responsible for a different aspect of the project.) Include
a 1 page executive summary which summarizes your decision.
Animal-to-Human Organ Transplantation
Peril or Promise?
Should animal
organs be used to deal with the organ shortage?
In this exercise,
you will be writing two press releases. One should be developed
by members of the Animal Liberation Front, regarding a recent
action taken against a private company's laboratory and farm allegedly
involved in the production of animals to harvest their organs.
The second press release should be issued by the private company,
responding to the charges and actions of the Animal Liberation
Front.
Each press release
should be 1-2 double-spaced pages.
A Presidential Commission on Embryonic Stem
Cells
Option 1:
Your group has been convened by the US President to issue a report
answering the following question: Should federal funds support experimental
research that involves the creation and cloning of embryonic stem
cells?
Your report
must address:
- The potential
benefits of embryonic stem cell research and whether these 'problems'
can be addressed by alternative means;
- The moral
status of embryos from at least three ethical standpoints;
- The history
of reproductive and genetic policies in the United States and
how this history does and should effect the current situation;
- What regulations
if any should be put in place;
- Issues of
access and affordability;
- Other issues
are they are pertinent to the discussion.
Each member
of your group must choose one of categories below and act
from within the boundaries of the chosen position (i.e., role-playing).
In your report,
please be sure to indicate where and why disagreements occur.
- Physician
- Spouse of
or a person diagnosed with Parkinson's Disease
- Religious
leader: please choose a faith; more than one religious leader's
participation may be necessary
- Members of
the public: a teacher, homemaker; social workers; retiree; and
so on; more than one member of the public should participate
- NIH administrator
- Embryonic
stem cell research advocate
- Medical researcher
- Bioethicist
- FDA policymaker
- Historian
of genetic and reproductive policies
- Sociologist
- Legal scholar
- Other options
must be approved by the instructor
Option 2:
You or you and your group will read and evaluate the September 1999
National Bioethics Advisory Committee Report: "Ethical Issues
in Human Stem Cell Research," available at http://www.georgetown.edu/research/nrcbl/nbac/pubs.html.
In your 4-5
page report, identify areas that NBAC must revisit due to scientific
and technological advances occurring in the years since the report
was drafted.
Organ and Body Part Manufacture and Repair
What does it mean to be human? How will the promise of bioengineering
- and cyborgs - change this meaning?
Imagine that
it is the year 2050. You, or you and your partner, are reporters
for Dateline. Prepare a transcript of your 15 minute report to
America on how bioengineering - specifically, organ and body part
manufacture and repair - has changed (or not changed) the face
of America. (Short commercials may be included as part of the
transcript.) Who will you interview? What types of evidence will
you gather? What questions will still remain open, if any?
You may be required
to present this report to your class in character.
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Review
Activities
Payment,
Trade, and Coercion Increasing the Number of Organ Donors
Encouraging Organ Donation A Commercial
Constructing Exam Questions on 'The Six Million
Dollar Body'
Organ Donation and the Popular Imagination
Payment,
Trade, and Coercion Increasing the Number of Organ Donors
The undersupply
of organs for transplantation is not a problem unique to the United
States. Global proposals beyond presumed consent,
xenotransplantation, mechanical organs and body parts, and stem
cells to increase the availability of organs for transplantation
include:
- the harvesting
of organs from executed prisoners;
- a reduction
in prison sentences for prisoners willing to donate kidneys or
livers;
- financial
incentives (including direct payment or funeral expenses); and
- preferred
status for organ donors or their families.
Prepare a 3-5
page brief evaluating each of these alternatives using the skills
and knowledge you have developed through your completion of this
module.
You may wish
to start here:
UNOS
Bioethics
http://www.unos.org/frame_Default.asp?Category=Resources
Encouraging Organ Donation A
Commercial
Develop a one
minute commercial encouraging organ donation for the American prime-time
public. Include both a script and descriptions of the actors and/or
visuals you would use.
Constructing Exam Questions on 'The Six Million
Dollar Body'
You, or you
and your partner must develop an exam to test your classmates' understanding
of the issues involved in this module. The exam should be worth
50 points, and include short answer, multiple choice, and at least
one essay question, among other testing mechanisms. Also develop
an 'answer sheet' for each question provide information regarding:
What types of information must be included for a 'complete' answer?
How many examples should be present? How much is each question worth?
How should your essay question be weighted? Please be sure to include
grammar and writing style as part of your grading calculation.
Organ
Donation and the Popular Imagination
Fiction writers
and filmmakers in the 19th and 20th centuries seem fascinated by
organ transplantation and body parts. From Frankenstein to
Invasion of the Body Snatchers to Return to Me (starring
Minnie Driver and David Duchovny), countless storytellers have imagined
both beautiful and horrific possibilities. They have asked even
more questions can souls and personalities be transplanted
with body parts? Do scientists have too much power to control life?
What constitutes death? What is the relationship between man and
machine? What does it mean to be human?
Locate two different
media dealing with organ transplantation and body parts films,
stories, books, video games, etc. and compare the stories
they tell and the questions asked. How do these narratives speak
to the scientific and ethical issues raised by the other sections
of the module?
Write a 3-4
page response paper.
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